Human Neurturin (NRTN) activation kit by CRISPRa

CAT#: GA103274

NRTN CRISPRa kit - CRISPR gene activation of human neurturin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NRTN
• Locus ID: 4902
• Kit Components:

  GA103274G1, Neurturin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103274G2, Neurturin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103274G3, Neurturin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004558
• Synonyms: NTN
• Summary: 'This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein signals through the RET receptor tyrosine kinase and a GPI-linked coreceptor, and promotes survival of neuronal populations. A neurturin mutation has been described in a family with Hirschsprung Disease. [provided by RefSeq, Aug 2016]'