Human DDR2 activation kit by CRISPRa

CAT#: GA103287

DDR2 CRISPRa kit - CRISPR gene activation of human discoidin domain receptor tyrosine kinase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DDR2
• Locus ID: 4921
• Kit Components:

  GA103287G1, DDR2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103287G2, DDR2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103287G3, DDR2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001014796, NM_006182, NM_001354982, NM_001354983
• Synonyms: MIG20a; NTRKR3; TKT; TYRO10
• Summary: 'This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironment. The encoded protein is a collagen-induced receptor that activates signal transduction pathways involved in cell adhesion, proliferation, and extracellular matrix remodeling. This protein is expressed in numerous cell types and may alos be involved in wound repair and regulate tumor growth and invasiveness. Mutations in this gene are the cause of short limb-hand type spondylometaepiphyseal dysplasia. [provided by RefSeq, Aug 2017]'