Human Neurotensin (NTS) activation kit by CRISPRa

CAT#: GA103288

NTS CRISPRa kit - CRISPR gene activation of human neurotensin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NTS
• Locus ID: 4922
• Kit Components:

  GA103288G1, Neurotensin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103288G2, Neurotensin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103288G3, Neurotensin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006183
• Synonyms: NMN-125; NN; NT; NT/N; NTS1
• Summary: 'This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Neurotensin also exhibits antimicrobial activity against bacteria and fungi. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active. [provided by RefSeq, Oct 2014]'