Human OAS3 activation kit by CRISPRa

CAT#: GA103300

OAS3 CRISPRa kit - CRISPR gene activation of human 2'-5'-oligoadenylate synthetase 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: OAS3
• Locus ID: 4940
• Kit Components:

  GA103300G1, OAS3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103300G2, OAS3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103300G3, OAS3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006187
• Synonyms: p100; p100OAS
• Summary: 'This gene encodes an enzyme included in the 2', 5' oligoadenylate synthase family. This enzyme is induced by interferons and catalyzes the 2', 5' oligomers of adenosine in order to bind and activate RNase L. This enzyme family plays a significant role in the inhibition of cellular protein synthesis and viral infection resistance. [provided by RefSeq, Jul 2008]'