Human PAFAH2 activation kit by CRISPRa

CAT#: GA103373

PAFAH2 CRISPRa kit - CRISPR gene activation of human platelet activating factor acetylhydrolase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PAFAH2
• Locus ID: 5051
• Kit Components:

  GA103373G1, PAFAH2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103373G2, PAFAH2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103373G3, PAFAH2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000437
• Synonyms: HSD-PLA2
• Summary: 'This gene encodes platelet-activating factor acetylhydrolase isoform 2, a single-subunit intracellular enzyme that catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). However, this lipase exhibits a broader substrate specificity than simply platelet activating factor. Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist, and both are multi-subunit enzymes. Additionally, there is a single-subunit serum isoform of this enzyme. [provided by RefSeq, Jul 2008]'