Human Peroxiredoxin 1 (PRDX1) activation kit by CRISPRa

CAT#: GA103374

PRDX1 CRISPRa kit - CRISPR gene activation of human peroxiredoxin 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PRDX1
• Locus ID: 5052
• Kit Components:

  GA103374G1, Peroxiredoxin 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103374G2, Peroxiredoxin 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103374G3, Peroxiredoxin 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001202431, NM_002574, NM_181696, NM_181697
• Synonyms: MSP23; NKEF-A; NKEFA; PAG; PAGA; PAGB; PRX1; PRXI; TDPX2
• Summary: 'This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Four transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jan 2011]'