Human PAX7 activation kit by CRISPRa

CAT#: GA103395

PAX7 CRISPRa kit - CRISPR gene activation of human paired box 7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PAX7
• Locus ID: 5081
• Kit Components:

  GA103395G1, PAX7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103395G2, PAX7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103395G3, PAX7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001135254, NM_002584, NM_013945
• Synonyms: HUP1; PAX7B; RMS2
• Summary: 'This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]'