Human PCDH1 activation kit by CRISPRa

CAT#: GA103408

PCDH1 CRISPRa kit - CRISPR gene activation of human protocadherin 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PCDH1
• Locus ID: 5097
• Kit Components:

  GA103408G1, PCDH1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103408G2, PCDH1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103408G3, PCDH1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001278613, NM_001278615, NM_002587, NM_032420
• Synonyms: PC42; PCDH42
• Summary: 'This gene belongs to the protocadherin subfamily within the cadherin superfamily. The encoded protein is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracelllular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene. [provided by RefSeq, Jul 2008]'