Human PCK2 activation kit by CRISPRa

CAT#: GA103415

PCK2 CRISPRa kit - CRISPR gene activation of human phosphoenolpyruvate carboxykinase 2, mitochondrial

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PCK2
• Locus ID: 5106
• Kit Components:

  GA103415G1, PCK2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103415G2, PCK2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103415G3, PCK2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001018073, NM_001291556, NM_004563, NM_001308054
• Synonyms: PEPCK; PEPCK-M; PEPCK2
• Summary: 'This gene encodes a mitochondrial enzyme that catalyzes the conversion of oxaloacetate to phosphoenolpyruvate in the presence of guanosine triphosphate (GTP). A cytosolic form of this protein is encoded by a different gene and is the key enzyme of gluconeogenesis in the liver. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2014]'