Human PDE6D activation kit by CRISPRa

CAT#: GA103444

PDE6D CRISPRa kit - CRISPR gene activation of human phosphodiesterase 6D

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PDE6D
• Locus ID: 5147
• Kit Components:

  GA103444G1, PDE6D gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103444G2, PDE6D gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103444G3, PDE6D gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001291018, NM_002601, NR_110994
• Synonyms: JBTS22; PDED
• Summary: 'This gene encodes the delta subunit of rod-specific photoreceptor phosphodiesterase (PDE), a key enzyme in the phototransduction cascade. A similar protein in cow functions in solubilizing membrane-bound PDE. In addition to its role in the PDE complex, the encoded protein is thought to bind to prenyl groups of proteins to target them to subcellular organelles called cilia. Mutations in this gene are associated with Joubert syndrome-22. Alternative splicing results in multiple splice variants. [provided by RefSeq, Mar 2014]'