Human CD31 (PECAM1) activation kit by CRISPRa

CAT#: GA103471

PECAM1 CRISPRa kit - CRISPR gene activation of human platelet and endothelial cell adhesion molecule 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PECAM1
• Locus ID: 5175
• Kit Components:

  GA103471G1, CD31 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103471G2, CD31 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103471G3, CD31 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000442
• Synonyms: CD31; CD31/EndoCAM; endoCAM; GPIIA; PECA1; PECAM-1
• Summary: 'The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. [provided by RefSeq, May 2010]'