Human PEX1 activation kit by CRISPRa

CAT#: GA103481

PEX1 CRISPRa kit - CRISPR gene activation of human peroxisomal biogenesis factor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PEX1
• Locus ID: 5189
• Kit Components:

  GA103481G1, PEX1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103481G2, PEX1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103481G3, PEX1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000466, NM_001282677, NM_001282678
• Synonyms: HMLR1; PBD1A; PBD1B; ZWS; ZWS1
• Summary: 'This gene encodes a member of the AAA ATPase family, a large group of ATPases associated with diverse cellular activities. This protein is cytoplasmic but is often anchored to a peroxisomal membrane where it forms a heteromeric complex and plays a role in the import of proteins into peroxisomes and peroxisome biogenesis. Mutations in this gene have been associated with complementation group 1 peroxisomal disorders such as neonatal adrenoleukodystrophy, infantile Refsum disease, and Zellweger syndrome. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013]'