Human PEX14 activation kit by CRISPRa

CAT#: GA103487

PEX14 CRISPRa kit - CRISPR gene activation of human peroxisomal biogenesis factor 14

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PEX14
• Locus ID: 5195
• Kit Components:

  GA103487G1, PEX14 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103487G2, PEX14 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103487G3, PEX14 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004565
• Synonyms: dJ734G22.2; NAPP2; PBD13A; Pex14p
• Summary: 'This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome. [provided by RefSeq, Jul 2008]'