Human PF4 activation kit by CRISPRa

CAT#: GA103488

PF4 CRISPRa kit - CRISPR gene activation of human platelet factor 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PF4
• Locus ID: 5196
• Kit Components:

  GA103488G1, PF4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103488G2, PF4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103488G3, PF4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002619, NM_001363352
• Synonyms: CXCL4; PF-4; SCYB4
• Summary: 'This gene encodes a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. The protein also exhibits antimicrobial activity against Plasmodium falciparum. [provided by RefSeq, Oct 2014]'