Human PFKL activation kit by CRISPRa

CAT#: GA103501

PFKL CRISPRa kit - CRISPR gene activation of human phosphofructokinase, liver type

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PFKL
• Locus ID: 5211
• Kit Components:

  GA103501G1, PFKL gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103501G2, PFKL gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103501G3, PFKL gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001002021, NM_002626, NR_024108
• Synonyms: ATP-PFK; PFK-B; PFK-L
• Summary: 'This gene encodes the liver (L) subunit of an enzyme that catalyzes the conversion of D-fructose 6-phosphate to D-fructose 1,6-bisphosphate, which is a key step in glucose metabolism (glycolysis). This enzyme is a tetramer that may be composed of different subunits encoded by distinct genes in different tissues. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]'