Human SERPINE2 activation kit by CRISPRa

CAT#: GA103539

SERPINE2 CRISPRa kit - CRISPR gene activation of human serpin family E member 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SERPINE2
• Locus ID: 5270
• Kit Components:

  GA103539G1, SERPINE2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103539G2, SERPINE2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103539G3, SERPINE2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001136528, NM_001136529, NM_001136530, NM_006216, NR_073116
• Synonyms: GDN; GDNPF; PI-7; PI7; PN-1; PN1; PNI
• Summary: 'This gene encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. Thrombin, urokinase, plasmin and trypsin are among the proteases that this family member can inhibit. This gene is a susceptibility gene for chronic obstructive pulmonary disease and for emphysema. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]'