Human SERPINB8 activation kit by CRISPRa

CAT#: GA103540

SERPINB8 CRISPRa kit - CRISPR gene activation of human serpin family B member 8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SERPINB8
• Locus ID: 5271
• Kit Components:

  GA103540G1, SERPINB8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103540G2, SERPINB8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103540G3, SERPINB8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001031848, NM_001276490, NM_002640, NM_198833, NM_001348367, NM_001348368, NM_001348369, NM_001348370, NR_145571, NM_001366198
• Synonyms: CAP2; PI8
• Summary: 'The protein encoded by this gene is a member of the ov-serpin family of serine protease inhibitors. The encoded protein is produced by platelets and can bind to and inhibit the function of furin, a serine protease involved in platelet functions. In addition, this protein has been found to enhance the mechanical stability of cell-cell adhesion in the skin, and defects in this gene have been associated with an autosomal-recessive form of exfoliative ichthyosis. [provided by RefSeq, Jan 2017]'