Human SERPINB9 activation kit by CRISPRa

CAT#: GA103541

SERPINB9 CRISPRa kit - CRISPR gene activation of human serpin family B member 9

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SERPINB9
• Locus ID: 5272
• Kit Components:

  GA103541G1, SERPINB9 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103541G2, SERPINB9 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103541G3, SERPINB9 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004155
• Synonyms: CAP-3; CAP3; PI-9; PI9
• Summary: 'This gene encodes a member of the serine protease inhibitor family which are also known as serpins. The encoded protein belongs to a subfamily of intracellular serpins. This protein inhibits the activity of the effector molecule granzyme B. Overexpression of this protein may prevent cytotoxic T-lymphocytes from eliminating certain tumor cells. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Mar 2012]'