Human SERPINI2 activation kit by CRISPRa

CAT#: GA103545

SERPINI2 CRISPRa kit - CRISPR gene activation of human serpin family I member 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SERPINI2
• Locus ID: 5276
• Kit Components:

  GA103545G1, SERPINI2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103545G2, SERPINI2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103545G3, SERPINI2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001012303, NM_006217
• Synonyms: MEPI; PANCPIN; PI14; TSA2004
• Summary: 'The gene encodes a member of a family of proteins that acts as inhibitors of serine proteases. These proteins function in the regulation of a variety of physiological processes, including coagulation, fibrinolysis, development, malignancy, and inflammation. Expression of the encoded protein may be downregulated during pancreatic carcinogenesis. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Jan 2013]'