Human PIGR activation kit by CRISPRa

CAT#: GA103550

PIGR CRISPRa kit - CRISPR gene activation of human polymeric immunoglobulin receptor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PIGR
• Locus ID: 5284
• Kit Components:

  GA103550G1, PIGR gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103550G2, PIGR gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103550G3, PIGR gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002644
• Synonyms: FLJ22667; MGC125361; MGC125362
• Summary: 'This gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene.[provided by RefSeq, Sep 2009]'