Human PI 3 Kinase catalytic subunit gamma (PIK3CG) activation kit by CRISPRa

CAT#: GA103559

PIK3CG CRISPRa kit - CRISPR gene activation of human phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PIK3CG
• Locus ID: 5294
• Kit Components:

  GA103559G1, PI 3 Kinase catalytic subunit gamma gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103559G2, PI 3 Kinase catalytic subunit gamma gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103559G3, PI 3 Kinase catalytic subunit gamma gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001282426, NM_001282427, NM_002649
• Synonyms: p110gamma; p120-PI3K; PI3CG; PI3K; PI3Kgamma; PIK3
• Summary: 'Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I catalytic subunit of PI3K. Like other class I catalytic subunits (p110-alpha p110-beta, and p110-delta), the encoded protein binds a p85 regulatory subunit to form PI3K. This gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2015]'