Human PI4KA activation kit by CRISPRa

CAT#: GA103562

PI4KA CRISPRa kit - CRISPR gene activation of human phosphatidylinositol 4-kinase alpha

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PI4KA
• Locus ID: 5297
• Kit Components:

  GA103562G1, PI4KA gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103562G2, PI4KA gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103562G3, PI4KA gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002650, NM_058004, NM_001362862, NM_001362863
• Synonyms: PI4K-ALPHA; pi4K230; PIK4CA
• Summary: 'This gene encodes a phosphatidylinositol (PI) 4-kinase which catalyzes the first committed step in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. The mammalian PI 4-kinases have been classified into two types, II and III, based on their molecular mass, and modulation by detergent and adenosine. The protein encoded by this gene is a type III enzyme that is not inhibited by adenosine. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2018]'