Human FXYD3 activation kit by CRISPRa

CAT#: GA103608

FXYD3 CRISPRa kit - CRISPR gene activation of human FXYD domain containing ion transport regulator 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FXYD3
• Locus ID: 5349
• Kit Components:

  GA103608G1, FXYD3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103608G2, FXYD3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103608G3, FXYD3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001136007, NM_001136008, NM_001136009, NM_001136010, NM_001136011, NM_001136012, NM_005971, NM_021910
• Synonyms: MAT8; PLML
• Summary: 'This gene belongs to a small family of FXYD-domain containing regulators of Na+/K+ ATPases which share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD, and containing 7 invariant and 6 highly conserved amino acids. This gene encodes a cell membrane protein that may regulate the function of ion-pumps and ion-channels. This gene may also play a role in tumor progression. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2008]'