Human PLS1 activation kit by CRISPRa

CAT#: GA103615

PLS1 CRISPRa kit - CRISPR gene activation of human plastin 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PLS1
• Locus ID: 5357
• Kit Components:

  GA103615G1, PLS1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103615G2, PLS1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103615G3, PLS1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001145319, NM_001172312, NM_002670
• Synonyms: I-PLASTIN; I isoform; Plastin-1; plastin 1; plastin 1 (I isoform)
• Summary: 'Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. The protein encoded by this gene is a third distinct plastin isoform, which is specifically expressed at high levels in the small intestine. Alternatively spliced transcript variants varying in the 5' UTR, but encoding the same protein, have been found for this gene. A pseudogene of this gene is found on chromosome 11.[provided by RefSeq, Feb 2010]'