Human Plexin A2 (PLXNA2) activation kit by CRISPRa

CAT#: GA103620

PLXNA2 CRISPRa kit - CRISPR gene activation of human plexin A2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PLXNA2
• Locus ID: 5362
• Kit Components:

  GA103620G1, Plexin A2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103620G2, Plexin A2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103620G3, Plexin A2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_025179
• Synonyms: OCT; PLXN2
• Summary: 'This gene encodes a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding during nervous system development. A subset of semaphorins are recognized by plexin-A/neuropilin transmembrane receptor complexes, triggering a cellular signal transduction cascade that leads to axon repulsion. This plexin-A family member is thought to transduce signals from semaphorin-3A and -3C. [provided by RefSeq, Jul 2008]'