Human PRRX1 activation kit by CRISPRa

CAT#: GA103635

PRRX1 CRISPRa kit - CRISPR gene activation of human paired related homeobox 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PRRX1
• Locus ID: 5396
• Kit Components:

  GA103635G1, PRRX1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103635G2, PRRX1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103635G3, PRRX1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006902, NM_022716
• Synonyms: AGOTC; PHOX1; PMX1; PRX-1; PRX1
• Summary: 'The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription co-activator, enhancing the DNA-binding activity of serum response factor, a protein required for the induction of genes by growth and differentiation factors. The protein regulates muscle creatine kinase, indicating a role in the establishment of diverse mesodermal muscle types. Alternative splicing yields two isoforms that differ in abundance and expression patterns. [provided by RefSeq, Jul 2008]'