Human DNA polymerase alpha (POLA1) activation kit by CRISPRa

CAT#: GA103645

POLA1 CRISPRa kit - CRISPR gene activation of human DNA polymerase alpha 1, catalytic subunit

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: POLA1
• Locus ID: 5422
• Kit Components:

  GA103645G1, DNA polymerase alpha gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103645G2, DNA polymerase alpha gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103645G3, DNA polymerase alpha gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_016937, NM_001330360
• Synonyms: NSX; p180; POLA
• Summary: 'This gene encodes the catalytic subunit of DNA polymerase, which together with a regulatory and two primase subunits, forms the DNA polymerase alpha complex. The catalytic subunit plays an essential role in the initiation of DNA replication. [provided by RefSeq, Mar 2010]'