Human POLR2H activation kit by CRISPRa

CAT#: GA103660

POLR2H CRISPRa kit - CRISPR gene activation of human RNA polymerase II subunit H

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: POLR2H
• Locus ID: 5437
• Kit Components:

  GA103660G1, POLR2H gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103660G2, POLR2H gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103660G3, POLR2H gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001278698, NM_001278699, NM_001278700, NM_001278714, NM_001278715, NM_006232, NM_001346879
• Synonyms: RPABC3; RPB8; RPB17
• Summary: 'The three eukaryotic RNA polymerases are complex multisubunit enzymes that play a central role in the transcription of nuclear genes. This gene encodes an essential and highly conserved subunit of RNA polymerase II that is shared by the other two eukaryotic DNA-directed RNA polymerases, I and III. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]'