Human RPB11 (POLR2J) activation kit by CRISPRa

CAT#: GA103662

POLR2J CRISPRa kit - CRISPR gene activation of human RNA polymerase II subunit J

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: POLR2J
• Locus ID: 5439
• Kit Components:

  GA103662G1, RPB11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103662G2, RPB11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103662G3, RPB11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006234
• Synonyms: hRPB14; POLR2J1; RPB11; RPB11A; RPB11m
• Summary: 'This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene exists as a heterodimer with another polymerase subunit; together they form a core subassembly unit of the polymerase. Two similar genes are located nearby on chromosome 7q22.1 and a pseudogene is found on chromosome 7p13. [provided by RefSeq, Jul 2008]'