Human POLR2L activation kit by CRISPRa

CAT#: GA103664

POLR2L CRISPRa kit - CRISPR gene activation of human RNA polymerase II subunit L

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: POLR2L
• Locus ID: 5441
• Kit Components:

  GA103664G1, POLR2L gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103664G2, POLR2L gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103664G3, POLR2L gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_021128
• Synonyms: hRPB7.6; RBP10; RPABC5; RPB7.6; RPB10; RPB10beta
• Summary: 'This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains four conserved cysteines characteristic of an atypical zinc-binding domain. Like its counterpart in yeast, this subunit may be shared by the other two DNA-directed RNA polymerases. [provided by RefSeq, Jul 2008]'