Human BRN4 (POU3F4) activation kit by CRISPRa

CAT#: GA103678

POU3F4 CRISPRa kit - CRISPR gene activation of human POU class 3 homeobox 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: POU3F4
• Locus ID: 5456
• Kit Components:

  GA103678G1, BRN4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103678G2, BRN4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103678G3, BRN4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000307
• Synonyms: BRAIN-4; BRN-4; BRN4; DFN3; DFNX2; OCT-9; OTF-9; OTF9
• Summary: 'This gene encodes a member of the POU-III class of neural transcription factors. This family member plays a role in inner ear development. The protein is thought to be involved in the mediation of epigenetic signals which induce striatal neuron-precursor differentiation. Mutations in this gene are associated with X chromosome-linked nonsyndromic mixed deafness. [provided by RefSeq, Dec 2012]'