Human CTSA activation kit by CRISPRa

CAT#: GA103694

CTSA CRISPRa kit - CRISPR gene activation of human cathepsin A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CTSA
• Locus ID: 5476
• Kit Components:

  GA103694G1, CTSA gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103694G2, CTSA gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103694G3, CTSA gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000308, NM_001127695, NM_001167594, NR_133656
• Synonyms: GLB2; GSL; NGBE; PPCA; PPGB
• Summary: 'This gene encodes a member of the peptidase S10 family of serine carboxypeptidases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate two chains that comprise the heterodimeric active enzyme. This enzyme possesses deamidase, esterase and carboxypeptidase activities and acts as a scaffold in the lysosomal multienzyme complex. Mutations in this gene are associated with galactosialidosis. [provided by RefSeq, Nov 2015]'