Human Protein Phosphatase 1 beta (PPP1CB) activation kit by CRISPRa

CAT#: GA103705

PPP1CB CRISPRa kit - CRISPR gene activation of human protein phosphatase 1 catalytic subunit beta

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PPP1CB
• Locus ID: 5500
• Kit Components:

  GA103705G1, Protein Phosphatase 1 beta gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103705G2, Protein Phosphatase 1 beta gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103705G3, Protein Phosphatase 1 beta gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002709, NM_206876, NM_206877
• Synonyms: HEL-S-80p; PP-1B; PP1B; PP1beta; PPP1CD
• Summary: 'The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Mouse studies suggest that PP1 functions as a suppressor of learning and memory. Two alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]'