Human IPP 2 (PPP1R2) activation kit by CRISPRa

CAT#: GA103708

PPP1R2 CRISPRa kit - CRISPR gene activation of human protein phosphatase 1 regulatory inhibitor subunit 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PPP1R2
• Locus ID: 5504
• Kit Components:

  GA103708G1, IPP 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103708G2, IPP 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103708G3, IPP 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001291504, NM_001291505, NM_001316325, NM_006241, NR_133014
• Synonyms: IPP-2; IPP2
• Summary: 'Protein phosphatase-1 (PP1) is one of the main eukaryotic serine/threonine phosphatases. The protein encoded by this gene binds to the catalytic subunit of PP1, strongly inhibiting its activity. Ten related pseudogenes have been found throughout the human genome. Several splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]'