Human PPP3CC activation kit by CRISPRa

CAT#: GA103732

PPP3CC CRISPRa kit - CRISPR gene activation of human protein phosphatase 3 catalytic subunit gamma

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PPP3CC
• Locus ID: 5533
• Kit Components:

  GA103732G1, PPP3CC gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103732G2, PPP3CC gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103732G3, PPP3CC gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001243974, NM_001243975, NM_005605
• Synonyms: CALNA3; CNA3; PP2Bgamma
• Summary: 'Calcineurin is a calcium-dependent, calmodulin-stimulated protein phosphatase involved in the downstream regulation of dopaminergic signal transduction. Calcineurin is composed of a regulatory subunit and a catalytic subunit. The protein encoded by this gene represents one of the regulatory subunits that has been found for calcineurin. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]'