Human PRB3 activation kit by CRISPRa

CAT#: GA103741

PRB3 CRISPRa kit - CRISPR gene activation of human proline rich protein BstNI subfamily 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PRB3
• Locus ID: 5544
• Kit Components:

  GA103741G1, PRB3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103741G2, PRB3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103741G3, PRB3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006249
• Synonyms: G1; PRG
• Summary: 'This gene encodes a member of the heterogeneous family of basic, proline-rich, human salivary glycoproteins. Multiple alleles of this gene exhibiting variations in the length of the tandem repeats have been identified. The reference genome encodes the "Long" allele. The protein isoforms encoded by this gene are recognized as the "first line of oral defense" against the detrimental effects of polyphenols in the diet and pathogen infections. This gene is located in a cluster of closely related salivary proline-rich proteins on chromosome 12. [provided by RefSeq, Nov 2015]'