Human PKIB activation kit by CRISPRa

CAT#: GA103762

PKIB CRISPRa kit - CRISPR gene activation of human cAMP-dependent protein kinase inhibitor beta

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PKIB
• Locus ID: 5570
• Kit Components:

  GA103762G1, PKIB gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103762G2, PKIB gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103762G3, PKIB gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001270393, NM_001270394, NM_001270395, NM_032471, NM_181794, NM_181795
• Synonyms: PRKACN2
• Summary: 'This gene encodes a member of the cAMP-dependent protein kinase inhibitor family. The encoded protein may play a role in the protein kinase A (PKA) pathway by interacting with the catalytic subunit of PKA, and overexpression of this gene may play a role in prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]'