Human DNA PKcs (PRKDC) activation kit by CRISPRa

CAT#: GA103781

PRKDC CRISPRa kit - CRISPR gene activation of human protein kinase, DNA-activated, catalytic subunit

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PRKDC
• Locus ID: 5591
• Kit Components:

  GA103781G1, DNA PKcs gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103781G2, DNA PKcs gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103781G3, DNA PKcs gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001081640, NM_006904
• Synonyms: DNA-PKcs; DNAPK; DNPK1; HYRC; HYRC1; IMD26; p350; XRCC7
• Summary: 'This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.[provided by RefSeq, Jul 2010]'