Human CGK2 (PRKG2) activation kit by CRISPRa

CAT#: GA103783

PRKG2 CRISPRa kit - CRISPR gene activation of human protein kinase cGMP-dependent 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PRKG2
• Locus ID: 5593
• Kit Components:

  GA103783G1, CGK2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103783G2, CGK2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103783G3, CGK2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001282480, NM_001282481, NM_001282482, NM_001282483, NM_001282485, NM_006259, NM_001363401
• Synonyms: cGK2; cGKII; PRKGR2
• Summary: 'This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein binds to and inhibits the activation of several receptor tyrosine kinases. The membrane-bound protein is a regulator of intestinal secretion, bone growth and renin secretion. Alternate splicing results in multiple transcript variants encoding distinct isoforms whose regulatory N-termini differ in length but whose C-terminal catalytic domains are identical. [provided by RefSeq, May 2018]'