Human MAPK11 activation kit by CRISPRa

CAT#: GA103790

MAPK11 CRISPRa kit - CRISPR gene activation of human mitogen-activated protein kinase 11

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MAPK11
• Locus ID: 5600
• Kit Components:

  GA103790G1, MAPK11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103790G2, MAPK11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103790G3, MAPK11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002751, NM_138993, NR_110887
• Synonyms: p38-2; P38B; p38Beta; P38BETA2; PRKM11; SAPK2; SAPK2B
• Summary: 'This gene encodes a member of a family of protein kinases that are involved in the integration of biochemical signals for a wide variety of cellular processes, including cell proliferation, differentiation, transcriptional regulation, and development. The encoded protein can be activated by proinflammatory cytokines and environmental stresses through phosphorylation by mitogen activated protein kinase kinases (MKKs). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]'