Human MEK1 (MAP2K1) activation kit by CRISPRa

CAT#: GA103794

MAP2K1 CRISPRa kit - CRISPR gene activation of human mitogen-activated protein kinase kinase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MAP2K1
• Locus ID: 5604
• Kit Components:

  GA103794G1, MEK1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103794G2, MEK1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103794G3, MEK1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002755
• Synonyms: CFC3; MAPKK1; MEK1; MKK1; PRKMK1
• Summary: 'The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. [provided by RefSeq, Jul 2008]'