Human PKR (EIF2AK2) activation kit by CRISPRa
CAT#: GA103800
EIF2AK2 CRISPRa kit - CRISPR gene activation of human eukaryotic translation initiation factor 2 alpha kinase 2
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | EIF2AK2 |
Locus ID | 5610 |
Kit Components | GA103800G1, PKR gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103800G2, PKR gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103800G3, PKR gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001135651, NM_001135652, NM_002759 |
Synonyms | EIF2AK1; PKR; PPP1R83; PRKR |
Summary | 'The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]' |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN210792 | EIF2AK2 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN210792BN | EIF2AK2 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN210792LP | EIF2AK2 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN210792RB | EIF2AK2 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN410792 | EIF2AK2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
{0} Product Review(s)
Be the first one to submit a review