Human PKR (EIF2AK2) activation kit by CRISPRa

CAT#: GA103800

EIF2AK2 CRISPRa kit - CRISPR gene activation of human eukaryotic translation initiation factor 2 alpha kinase 2

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Find the corresponding CRISPRi Inhibitor Kit

USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Frequently bought together (1)
qSTAR qPCR primer pairs against Homo sapiens gene EIF2AK2
    • 200 reactions

USD 120.00

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol EIF2AK2
Locus ID 5610
Kit Components

GA103800G1, PKR gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103800G2, PKR gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103800G3, PKR gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001135651, NM_001135652, NM_002759
Synonyms EIF2AK1; PKR; PPP1R83; PRKR
Summary 'The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]'

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.