Human PRODH activation kit by CRISPRa

CAT#: GA103811

PRODH CRISPRa kit - CRISPR gene activation of human proline dehydrogenase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PRODH
• Locus ID: 5625
• Kit Components:

  GA103811G1, PRODH gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103811G2, PRODH gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103811G3, PRODH gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001195226, NM_016335
• Synonyms: HSPOX2; PIG6; POX; PRODH1; PRODH2; TP53I6
• Summary: 'This gene encodes a mitochondrial protein that catalyzes the first step in proline degradation. Mutations in this gene are associated with hyperprolinemia type 1 and susceptibility to schizophrenia 4 (SCZD4). This gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes, DiGeorge and CATCH22. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2010]'