Human Trypsin (PRSS1) activation kit by CRISPRa

CAT#: GA103824

PRSS1 CRISPRa kit - CRISPR gene activation of human serine protease 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PRSS1
• Locus ID: 5644
• Kit Components:

  GA103824G1, Trypsin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103824G2, Trypsin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103824G3, Trypsin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002769
• Synonyms: TRP1; TRY1; TRY4; TRYP1
• Summary: 'This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of lysine or arginine. Mutations in this gene are associated with hereditary pancreatitis. This gene and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7. [provided by RefSeq, Jul 2008]'