Human HTRA1 activation kit by CRISPRa

CAT#: GA103833

HTRA1 CRISPRa kit - CRISPR gene activation of human HtrA serine peptidase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HTRA1
• Locus ID: 5654
• Kit Components:

  GA103833G1, HTRA1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103833G2, HTRA1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103833G3, HTRA1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002775
• Synonyms: ARMD7; CADASIL2; CARASIL; HtrA; L56; ORF480; PRSS11
• Summary: 'This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7. [provided by RefSeq, Jul 2008]'