Human PSG9 activation kit by CRISPRa

CAT#: GA103848

PSG9 CRISPRa kit - CRISPR gene activation of human pregnancy specific beta-1-glycoprotein 9

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PSG9
• Locus ID: 5678
• Kit Components:

  GA103848G1, PSG9 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103848G2, PSG9 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103848G3, PSG9 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001301707, NM_001301708, NM_001301709, NM_002784
• Synonyms: PS34; PSBG-9; PSBG-11; PSG11; PSGII
• Summary: 'The protein encoded by this gene is a member of the pregnancy-specific glycoprotein (PSG) family. This protein family and the closely related carcinoembryonic antigen cell adhesion molecule (CEACAM) gene family are both members of the immunoglobulin superfamily, and are organized as a large gene cluster. This protein is thought to inhibit platelet-fibrinogen interactions. Several studies suggest that reduced serum concentrations of PSGs are associated with fetal growth restrictions, while up-regulation of this gene has been observed in colorectal cancers. Several pseudogenes of this gene are found on chromosome 19. Alternative splicing results in multiple transcript variants that encode multiple protein isoforms. [provided by RefSeq, Sep 2014]'