Human Nectin 2 (NECTIN2) activation kit by CRISPRa

CAT#: GA103957

NECTIN2 CRISPRa kit - CRISPR gene activation of human nectin cell adhesion molecule 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NECTIN2
• Locus ID: 5819
• Kit Components:

  GA103957G1, Nectin 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103957G2, Nectin 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103957G3, Nectin 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001042724, NM_002856
• Synonyms: CD112; HVEB; PRR2; PVRL2; PVRR2
• Summary: 'This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]'