Human PYCR1 activation kit by CRISPRa

CAT#: GA103966

PYCR1 CRISPRa kit - CRISPR gene activation of human pyrroline-5-carboxylate reductase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PYCR1
• Locus ID: 5831
• Kit Components:

  GA103966G1, PYCR1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103966G2, PYCR1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103966G3, PYCR1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001282279, NM_001282280, NM_001282281, NM_001330523, NM_006907, NM_153824
• Synonyms: ARCL2B; ARCL3B; P5C; P5CR; PIG45; PP222; PRO3; PYCR
• Summary: 'This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]'