Human RAB27A activation kit by CRISPRa

CAT#: GA103987

RAB27A CRISPRa kit - CRISPR gene activation of human RAB27A, member RAS oncogene family

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RAB27A
• Locus ID: 5873
• Kit Components:

  GA103987G1, RAB27A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103987G2, RAB27A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103987G3, RAB27A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004580, NM_183234, NM_183235, NM_183236
• Synonyms: GS2; HsT18676; RAB27; RAM
• Summary: 'The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]'