Human RABGGTB activation kit by CRISPRa

CAT#: GA103990

RABGGTB CRISPRa kit - CRISPR gene activation of human Rab geranylgeranyltransferase subunit beta

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RABGGTB
• Locus ID: 5876
• Kit Components:

  GA103990G1, RABGGTB gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103990G2, RABGGTB gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103990G3, RABGGTB gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004582, NR_073562
• Synonyms: GGTB
• Summary: 'This gene encodes the beta-subunit of the enzyme Rab geranylgeranyl-transferase (RabGGTase), which belongs to the protein prenyltransferase family. RabGGTase catalyzes the post-translational addition of geranylgeranyl groups to C-terminal cysteine residues of Rab GTPases. Three small nucleolar RNA genes are present in the intronic regions of this gene. Alternately spliced transcript variants have been observed for this gene. A pseudogene associated with this gene is located on chromosome 3. [provided by RefSeq, Jan 2013]'